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Lenovo ThinkPad P16s Gen 4 - 16-Inch Mobile Workstation, Intel Core Ultra 7 255H, NVIDIA RTX PRO 500, 32GB DDR5, 1TB SSD (21QV003LUS)

SKU: 21QV003LUS

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16-Inch Mobile Workstation with Intel Core Ultra 7 255H, NVIDIA RTX PRO 500 Blackwell 6GB GDDR7, 32GB DDR5-6400 Expandable to 96GB, and Premier Support at 4.01 Pounds

The Lenovo ThinkPad P16s Gen 4 (21QV003LUS) is a 16-inch mobile workstation laptop built on Intel's Core Ultra 7 2nd Gen 255H processor with NVIDIA RTX PRO 500 Blackwell Generation discrete graphics backed by 6GB of GDDR7 memory, 32GB of DDR5-6400 memory expandable to 96GB, a 1TB M.2 SSD, and WiFi 7 (802.11be) connectivity in a 4.01-pound aluminum chassis.

The Core Ultra 7 255H delivers 16 cores and 16 threads with boost speeds up to 5.10 GHz, paired with Intel AI Boost providing 13 TOPS of NPU performance for on-device AI workloads. The NVIDIA RTX PRO 500 Blackwell Generation GPU provides 6GB of dedicated GDDR7 memory for ISV-certified application performance, GPU-accelerated rendering, and professional visualization workflows that integrated graphics cannot sustain. The 32GB DDR5-6400 memory ships as a single 32GB CSODIMM with one free slot, allowing expansion to 96GB without replacing existing memory.

The 16-inch WUXGA (1920x1200) IPS anti-glare display produces 400 nits of brightness at 60Hz with a 16:10 aspect ratio, delivering 27% more screen area than 14-inch models for spreadsheet-heavy and multi-window workflows. The low blue light panel reduces eye strain during extended work sessions. The combination of NVIDIA RTX PRO dedicated graphics and a 16-inch display provides a workstation platform for professionals running CAD, BIM, and simulation applications that demand certified GPU performance and large-format screen real estate.

The 1TB M.2 SSD provides ample storage for applications, project files, and datasets, with the M.2 slot supporting user-replaceable storage upgrades. WiFi 7 (802.11be) delivers next-generation wireless throughput, and Gigabit Ethernet via the built-in RJ-45 port provides wired connectivity. An IR camera enables Windows Hello facial recognition alongside the fingerprint reader for dual biometric authentication. Premier Support provides direct access to advanced Lenovo technicians for priority issue resolution.

Where the ThinkPad P16s Gen 4 21QV003LUS Fits

  • Engineers and designers running ISV-certified workstation applications on a 16-inch display where the NVIDIA RTX PRO 500 Blackwell GPU with 6GB GDDR7 delivers certified performance for CAD, BIM, and simulation workflows alongside the screen area needed for multi-pane design environments
  • IT departments deploying Intel-platform mobile workstations with dedicated GPU performance where the Core Ultra 7 255H, DDR5-6400 memory with one free expansion slot, and 1TB SSD provide a high-performance workstation base with upgrade headroom to 96GB
  • Mobile professionals who need dedicated GPU workstation performance in a 16-inch form factor where the 4.01-pound aluminum chassis delivers NVIDIA RTX PRO graphics, a 16-inch anti-glare display, the full ThinkPad port array, and Premier Support

What the ThinkPad P16s Gen 4 21QV003LUS Delivers

  • Intel Core Ultra 7 255H with 13 TOPS NPU: 16 cores, 16 threads, up to 5.10 GHz with Intel AI Boost neural processing delivering 13 TOPS for on-device AI workloads.
  • NVIDIA RTX PRO 500 Blackwell, 6GB GDDR7: Dedicated professional GPU with 6GB of GDDR7 memory for ISV-certified CAD, rendering, and visualization performance.
  • 32GB DDR5-6400, Expandable to 96GB: Ships with 1x32GB CSODIMM and one free slot, allowing expansion to 96GB without replacing existing memory.
  • 16-Inch WUXGA IPS Anti-Glare, 400 nit: 1920x1200 resolution in a 16:10 aspect ratio with 400-nit brightness, anti-glare coating, and low blue light technology for comfortable extended viewing.
  • 1TB M.2 SSD: Fast NVMe storage for applications, project files, and datasets with user-replaceable M.2 slot for future upgrades.
  • 4.01 lb Aluminum Build with Premier Support: Aluminum cover chassis at 4.01 pounds with dual biometric authentication, full port array including Thunderbolt 4 and RJ-45, 100W USB-C charging, and Premier Support for direct access to advanced technicians.

Overview

Product: ThinkPad P16s Gen 4 (21QV003LUS)

Brand: Lenovo

Product Line: ThinkPad P Series

Part Number: 21QV003LUS

Release Date: September 2025

Processor

CPU: Intel Core Ultra 7 2nd Gen 255H

Cores/Threads: 16 Cores / 16 Threads

Max Turbo Frequency: 5.10 GHz

Platform: Intel

NPU: Intel AI Boost, 13 TOPS

Graphics

GPU: NVIDIA RTX PRO 500 Blackwell Generation

GPU Memory: 6 GB GDDR7 (Dedicated)

Memory

Installed RAM: 32 GB DDR5-6400

Configuration: 1x 32GB CSODIMM (1 slot free)

Max Supported: 96 GB (2 slots)

Storage

SSD: 1 TB M.2 PCIe NVMe

Display

Size: 16 inches

Resolution: 1920 x 1200 (WUXGA)

Panel Type: IPS

Refresh Rate: 60 Hz

Brightness: 400 nit

Color Gamut: 45% NTSC

Touch: No

Features: Anti-Glare, Low Blue Light

Networking

WiFi: WiFi 7 (802.11be)

Bluetooth: Yes

Ethernet: Gigabit Ethernet (RJ-45)

Ports & Slots

Thunderbolt: 2x Thunderbolt 4 (USB-C)

USB-A: 2x USB 3.2 Gen 1 Type-A

Video Output: HDMI

Network: RJ-45 Ethernet

Camera & Security

Camera: 5MP with IR

Privacy: Physical Shutter

Biometrics: IR Camera + Fingerprint Reader

Input

Keyboard: Backlit, English

Power & Physical

AC Adapter: 100W USB-C

Weight: 4.01 lb (1.82 kg)

Dimensions: 14.2 x 9.8 x 1.0 in

Color: Black

Material: Aluminum

Operating System

OS: Windows 11 Pro

Certifications

Environmental: ENERGY STAR 9.0, EPEAT Gold, TCO Certified 10.0, RoHS

Warranty

Coverage: 1 Year Manufacturer Warranty (Courier/Carry-in) + Premier Support

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