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Lenovo ThinkPad P16s Gen 4 - 16-Inch OLED Touchscreen Mobile Workstation, AMD Ryzen AI 7 PRO 350, 64GB DDR5, 1TB SSD (21QR001DUS)

SKU: 21QR001DUS

Regular price $4,492.99 USD
Regular price Sale price $4,492.99 USD
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16-Inch WQUXGA OLED Touchscreen Mobile Workstation with AMD Ryzen AI 7 PRO 350, 50 TOPS XDNA 2 NPU, 100% DCI-P3, 64GB DDR5, and Premier Support at 3.77 Pounds

The Lenovo ThinkPad P16s Gen 4 (21QR001DUS) is a 16-inch Copilot+ PC mobile workstation laptop built on AMD's Ryzen AI 7 PRO 350 processor with a 50 TOPS XDNA 2 neural processing unit, AMD Radeon 860M graphics, 64GB of DDR5-5600 memory expandable to 96GB, a 1TB M.2 SSD, and a WQUXGA (3840x2400) OLED touchscreen covering 100% of the DCI-P3 color gamut in a 3.77-pound carbon fiber and glass fiber chassis.

The Ryzen AI 7 PRO 350 delivers 8 cores and 16 threads with boost speeds up to 5.00 GHz, paired with AMD's XDNA 2 NPU rated at 50 TOPS for Copilot+ PC certification and on-device AI processing. The PRO designation provides AMD PRO security features and manageability for IT-managed fleet deployments. The 64GB DDR5-5600 memory ships as two 32GB SoDIMMs occupying both slots, with a maximum supported capacity of 96GB for workstation-class multitasking demands.

The 16-inch WQUXGA OLED touchscreen produces 3840x2400 resolution at 400 nits with 100% DCI-P3 color coverage, Eyesafe certification for reduced blue light exposure, and anti-reflection and anti-smudge coatings. The 16:10 aspect ratio in a 4K-class OLED panel delivers the color accuracy and pixel density required for design review, photo editing, and content creation workflows where IPS panels fall short. AMD Radeon 860M integrated graphics handle multi-display output and hardware-accelerated video encoding.

The 1TB M.2 SSD provides working storage for large project files and datasets, with the M.2 slot supporting user-replaceable storage upgrades. WiFi 7 (802.11be) delivers next-generation wireless throughput, and Gigabit Ethernet via the built-in RJ-45 port provides wired connectivity. An IR camera enables Windows Hello facial recognition alongside the fingerprint reader for dual biometric authentication. The included 100W USB-C adapter powers the higher-resolution OLED display and workstation-class components, and Premier Support provides direct access to advanced Lenovo technicians.

Where the ThinkPad P16s Gen 4 21QR001DUS Fits

  • Creative professionals and designers who need color-accurate OLED in a portable workstation where the 3840x2400 OLED touchscreen with 100% DCI-P3 delivers the color gamut coverage and contrast ratio required for photo editing, design review, and content proofing without an external reference monitor
  • Organizations deploying AI-capable mobile workstations with PRO manageability where the Ryzen AI 7 PRO 350 with 50 TOPS XDNA 2 NPU provides Copilot+ PC features alongside AMD PRO security, and 64GB of DDR5 memory supports data-intensive workloads including large datasets and virtualized environments
  • Mobile professionals who need large-screen workstation performance under 4 pounds where the 3.77-pound carbon fiber and glass fiber chassis delivers 16 inches of 4K OLED display area with the full ThinkPad port array, Premier Support, and workstation-grade memory capacity up to 96GB

What the ThinkPad P16s Gen 4 21QR001DUS Delivers

  • AMD Ryzen AI 7 PRO 350 with 50 TOPS NPU: 8 cores, 16 threads, up to 5.00 GHz with AMD XDNA 2 neural processing delivering 50 TOPS for Copilot+ PC certification and AMD PRO security and manageability.
  • 64GB DDR5-5600, Expandable to 96GB: Ships with 2x32GB SoDIMMs for dual-channel performance, with maximum supported capacity of 96GB for workstation-class multitasking.
  • 16-Inch WQUXGA OLED Touchscreen, 100% DCI-P3: 3840x2400 resolution OLED panel with 400-nit brightness, 100% DCI-P3 color gamut, Eyesafe certification, and anti-reflection coating for color-critical workflows.
  • 1TB M.2 SSD: Fast NVMe storage for large project files, datasets, and applications with user-replaceable M.2 slot for future upgrades.
  • Thunderbolt 4 + Full Port Array: 2x Thunderbolt 4 (USB-C), 2x USB 3.2 Gen 1 Type-A, HDMI, and RJ-45 provide docking, display output, and peripheral connectivity without adapters.
  • 3.77 lb Carbon Fiber Build with Premier Support: Carbon fiber and glass fiber chassis at 3.77 pounds with 100W USB-C charging, dual biometric authentication, and Premier Support for direct access to advanced technicians.

Overview

Product: ThinkPad P16s Gen 4 (21QR001DUS)

Brand: Lenovo

Product Line: ThinkPad P Series

Part Number: 21QR001DUS

Release Date: May 2025

Copilot+ PC: Yes

Processor

CPU: AMD Ryzen AI 7 PRO 350

Cores/Threads: 8 Cores / 16 Threads

Base Clock: 2.00 GHz

Max Turbo Frequency: 5.00 GHz

Platform: AMD

NPU: AMD Ryzen AI (XDNA 2), 50 TOPS

Memory

Installed RAM: 64 GB DDR5-5600

Configuration: 2x 32GB SoDIMM (0 slots free)

Max Supported: 96 GB (2 slots)

Storage

SSD: 1 TB M.2 PCIe NVMe

Display

Size: 16 inches

Resolution: 3840 x 2400 (WQUXGA)

Panel Type: OLED

Brightness: 400 nit

Color Gamut: 100% DCI-P3

Touch: Yes

Features: Eyesafe, Anti-Reflection, Anti-Smudge, Low Blue Light

Graphics

GPU: AMD Radeon 860M (Integrated)

GPU Memory: Shared (DDR5)

Networking

WiFi: WiFi 7 (802.11be)

Bluetooth: Yes

Ethernet: Gigabit Ethernet (RJ-45)

Ports & Slots

Thunderbolt: 2x Thunderbolt 4 (USB-C)

USB-A: 2x USB 3.2 Gen 1 Type-A

Video Output: HDMI

Network: RJ-45 Ethernet

Camera & Security

Camera: 5MP with IR

Privacy: Physical Shutter

Biometrics: IR Camera + Fingerprint Reader

Input

Keyboard: Backlit, English

Power & Physical

AC Adapter: 100W USB-C

Weight: 3.77 lb (1.71 kg)

Dimensions: 14.2 x 9.9 x 0.93 in

Color: Black

Material: Carbon Fiber / Polycarbonate / Glass Fiber

Operating System

OS: Windows 11 Pro

Certifications

Environmental: ENERGY STAR 9.0, EPEAT Gold, TCO Certified 10.0, RoHS

Warranty

Coverage: 1 Year Manufacturer Warranty (Courier/Carry-in) + Premier Support

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